

CONSIDERATIONS | SUSPECTED SJS, TEN, OR DRESS | CONFIRMED SJS, TEN, OR DRESS |
---|---|---|
Dose modification with Opdualag |
Withhold treatment | Permanently discontinue treatment |
Management | Topical emollients and/or topical corticosteroids may be adequate to treat mild to moderate nonexfoliative rashes. Administer 1 to 2 mg/kg/day prednisone or equivalent until improvement to Grade 1 or less. Upon improvement to Grade 1 or less, initiate corticosteroid taper and continue to taper over at least 1 month. |
|
Follow-up | Consider administration of other systemic immunosuppressants, including corticosteroid therapy, if clinically appropriate. |
DRESS=drug rash with eosinophilia; SJS=Stevens-Johnson syndrome; TEN=toxic epidermal necrolysis.
Learn more about the dosing schedule for this fixed-dose combination therapy.
A convenient, printable tool to help nurses identify signs and symptoms of immune-mediated adverse reactions.
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